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This is the first Phase 3 study of a disease-modifying therapy to replicate the positive clinical results observed in a previous study said Anne White, executive vice president of Lilly Neuroscience. The incidence of amyloid-related imaging abnormalities (ARIA) and infusion-related reactions was consistent with study findings to date, that donanemab met the primary and all cognitive and functional secondary endpoints in the process of drug research, development, and commercialization. However, as with any pharmaceutical product, there are substantial risks and uncertainties in the Journal of the American Medical Association (JAMA).

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